Studying the levels of some vital parameters in patients with renal failure in Damascus

Abstract

Background: Chronic inflammation is considered one of the most important pathological assets in patients with renal failure as well as patients with hemodialysis and one of the most important risk factors predisposing to the incidence of the disease, it's progression and the development of its complications. Inflammation plays an important role in the pathophysiology of many complications, the most important of which are: Anemia, where anemia is a common complication in patients with Hemodialysis. The aim of this study is to evaluation the inflammatory status and renal function and to evaluate the parameters of anemia in patients with renal failure and Hemodialysis patients.

Materials and methods: Venous blood samples were collected from patients, and the following laboratory analyzes were performed: CRP, Cr, HGB, HCT, MCV and MCH.

Results: As a result of the study, it was found that there was a state of chronic inflammation and anemia in all patients of the study. There was a statistically significant difference (P<0.05) in the values of CRP, Cr, HGB, HCT, MCV, and MCH in the diseased groups compared to the healthy group. A statistically significant difference was observed in the values of HGB, HCT, MCV, MCH and Cr in the hemodialysis group compared to the renal failure group, while there was no statistically significant difference in the CRP values in the hemodialysis group compared to the renal failure group.

Conclusions: The inflammatory state of the patients is due to the progression of the renal failure itself, as it was noted that there was no statistically significant effect of the hemodialysis process on the inflammatory state of the patients, while the hemodialysis process had a clear effect on the development of anemia in patients.

Keywords: Hemodialysis, Renal Failure, Anemia, Inflammation, Hemoglobin, C-Reactiveeprotein.