The efficacy of different drugs in treatment the denture-related traumatic ulcerations:RCT

Abstract

Background & Aim: Placement of a complete denture is not the final step in the treatment of edentulous patients and patient's visit to the dentist continues long after that. Traumatic mucosal ulcerations are among the most common complaints of edentulous patients after placement of complete dentures. Ulcers are painful and result in patient discomfort. As a result, patients are no longer willing to wear their dentures and develop a feeling of mistrust toward their dentist and his/her treatment plan. Various factors are responsible for mucosal injuries among which denture base defects, like overextension of the flanges, improper adaptation of internal surface of the denture with underlying  soft tissues, denture irregularities, porosities or tissue undercuts and presence of immature occlusal contact are the most common. The abovementioned defects are usually due to clinical or laboratory errors during various stages of denture fabrication, including border molding, impression taking, and inadequate or insufficient polishing of the denture

The aim of this study to evaluate the effects of different medical subjects  on healing rate of traumatic ulcerations during a 2-week period after placement of new complete dentures.

Materials and methods: eighty edentulous patients were enrolled in this clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 3 days after denture placement

Then after 3,7, and 14 days after treatment. The sample was randomly divided to 4 groups . Group A was treated with kenalog , group B was treated with biravex, group C was treated with salt solution ,and group D was the control group. At each visit  healing of ulceration was graded by a clinician.

Results: Removing the cause agent  of traumatic ulcerations causing by new dentures is the most important procedure in increasing  healing rate. When comparing the healing rate after three days and one week of treatment between each group the results were as follows: healing rate in both of group A and B was higher than group C and D .

Conclusion: It`s advised to use medical materials such as kenalog or piravex after placement of new dentures and removing the cause agent of traumatic ulcers.