ال القيمة الإنذارية لمستوى ألبومين المصل في التنبؤ بالوفيات داخل المستشفى لدى مرضى ذات الرئة الاستنشاقية

Abstract

Background & Aim: The predictive value of serum albumin in adult aspiration pneumonia patients remains unknown.  This study aimed to determine whether the serum albumin is a prognostic biomarker of mortality in patients with aspiration pneumonia.

Materials and Methods: A Prospective cohort study included 75 patients diagnosed with aspiration pneumonia who had been admitted to the University Hospitals in Damascus  via the emergency department (ED) during the period from 1/10/2019 to31/6/2021. we evaluated the predictive value of serum albumin level at ED presentation for in-hospital mortality .The data of the non-hypoalbuminemia group and hypoalbuminemia group were compared. The data was analyzed using the statistical analysis program(SPSS) version (17) and the variable was considered statistically significant when the P-Value is less than (0.05(.

Results: A final diagnosis of aspiration pneumonia was made for 75 patients during the study period. The mean age of participants was 66±15.The number of males was 49 (65.3%) and females 26 (34%) .The mean serum albumin level was 3.23±0.56 g/dl. Overall,30 cases died (40%).The area under the receiver operating characteristics (AUROC) for in-hospital survival was 0.862 (95% CI 0.78-0.94). High sensitivity (70%) and high specificity ( 93%) was shown at level of 3.250 g/dl.

Conclusions: Initial serum albumin levels were independently associated with in-hospital mortality among adult patients hospitalized with aspiration pneumonia.