Synthesis Of New Schiff Bases Derived From Reaction Of Fluorene -2- Aldehyde With Hetero Cyclic Amines, And Study Their Antioxidant Activity

Abstract

This research deals with the synthesis of new derivatives of Schiff's basis with anti-oxidant activity, namely: (I) 2,2'-difluorenylidene) 3,5-diamino 1,2,4-triazole, and the (II) derivative 5-mercapto- N-(2-Fluorenylidene) amino 1,3,4- thiazoles from the reaction of fluorine aldehyde with some different heterocyclic amines. The methods of synthesis of these compounds, and determination of their physical properties and constants were carried out physical constants. The synthetic compounds were identified by infrared spectroscopy (FT-IR) and mass spectrometry (LC-MS). Its anti-oxidant efficacy was tested by measuring its ability to scavenge free radical DPPH^.. The percentage of free radical scavenging of the prepared compounds was calculated and their results were compared with a standard series of ascorbic acid.