Does the application of leukocyte and platelet rich fibrin have importance in reducing post-operative pain?

Abstract

Aim and background: post-operative pain is considered one of the most important challenges that faces the dentist, many materials and techniques have been employed for this purpose, but none of them has been proved as the best.

Objective: to assess the effectiveness of leukocyte and platelet rich fibrin in reducing post-operative pain.

Materials and methods: the study has included 20 patients in need of symmetrical extraction of maxillary and mandibular premolars by the application of leukocyte and platelet rich fibrin in test sockets and unassisted healing in control sockets, suturing both sockets with cross-sutures and randomization of the test and control sockets. The patients were followed-up for one week for the assessment of post-operative pain by studying visual analog scale VAS values during the first and second days.

Results: the study showed statistically significant differences in reducing post-operative pain by using leukocyte and platelet rich fibrin.

Conclusions: the use of leukocyte and platelet rich fibrin has an effective role in reducing post-operative pain.