Effect of Bioactive glass on efficacy and post-operative sensitivity of vital teeth bleaching: Randomized Controlled Clinical Trial

Abstract

Background and aim: To evaluate the effect of bioactive glass 45S5 (BAG) on color change and tooth sensitivity (TS) associated with at-home vital tooth bleaching using 20% carbamide peroxide (CP).

Materials and methods: A randomized double-blinded controlled clinical trial was conducted to measure the TS and tooth color change of 24 patients at 3-day, 7-day, 14-day, 1month, 3months, and 6months periods. The participants were instructed to apply 20% CP (7 days-04 h each) followed by the application of either bioactive glass 45S5 paste or non-active placebo paste, delivered by the bleaching custom tray (7 days-30 min each). Lightness (L*), redness (a*) and yellowness (b*) were measured using a digital spectrophotometer and the overall color changes ΔE were calculated. TS was evaluated daily for 7 days by the patients themselves using visual analogue scale (VAS). ΔE and TS values were statistically analyzed using SPSS V25. The level of statistical significance was established at p = 0.05.

Results: No significant differences were detected between bioactive glass 45S5 (BAG) and placebo groups regarding the ΔE at p-value = 0.05. The BAG application doesn't reduce the TS reported by the participants when compared with the placebo group.

Conclusion: The association of BAG did not affect the color change induced by tooth bleaching.

Keywords: Bioactive Glass 45S5 (BAG), Bleaching, Teeth Sensitivity.