Assessment of right ventricle function in pulmonary hypertension secondary to congenital heart diseases with (left to right) shunt in children using TAPSE TDI(s`)

Abstract

Bakground & Aim: pulmonary arterial hypertension (PAH) is a frequent complication of congenital heart disease (CHD), particularly in patients with left-to-right (systemic-to-pulmonary) shunts, especially those who are not subject to timely surgical repair. Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure (MPAP) > 25 mm Hg at rest or > 30 mm Hg during exercise measured by cardiac catheterization, or a systolic pulmonary artery pressure (SPAP) > 40 mm Hg measured by echocardiography.

The aim of the study is to establish the relationship between the pulmonary arterial hypertension related to congenital heart disease with left to right shunt and the systolic function of right ventricle using echocardiography, also to study the systolic function of right ventricle in cases of pulmonary arterial hypertension related to congenital heart disease with left to right shunt to determine the diagnosis and the type of management.

Materials and Methods: prospective cohort study, took a place in Children’s University Hospital in Damascus from 1/3/2020 to 1/3/2021. It included 60 children with pulmonary arterial hypertension secondary to congenital heart disease with left to right shunt.

Results: There was a statistically significant relationship between pulmonary hypertension and TAPSE, and between pulmonary hypertension and systolic wave velocity (S’), measured by pulsed Doppler tissue imaging(TDI). Also there are reverse fit between pulmonary hypertension and (TAPSE&TDIs').