New Prognostic Factors for Local Recurrence in Cutaneous Basal Cell Carcinoma

Abstract

Background: BCC is an epithelial malignant tumor with a low malignant potential. It is a slow growing tumor, which rarely metastasizes but can cause substantial morbidity due to its location on the face, its tendency to relapse, its multiplicity and the potential to invade and destroy local tissues. It forms a group of   hetergenous  tumors range from superficial to deeply invasive tumors. Histological type, anatomic site and tumor size may be have prognostic role, but the information and researches about them still scant.

Methods: It is a descriptive study (cross sectional study). The study included 87 cases of  basal cell carcinoma. Data were obtained from archives of the pathology department, at Almouwasat  University Hospital in 2018 with follow up to evaluate the local recurrence.

Results: There was a significant positive relation between local recurrence and anatomic site and histological type (P<0.0001 for each), but there was no significant relation between local recurrence and tumor size (Sig=0.813).

Conclusion: It is crucial to evaluate risk factors such as basal cell carcinoma  subtype and localization, as these are associated with a higher rate of recurrence. These risk factors, together with pre-treatment lesion evaluation will enable formulation of  better treatment plan and prognostic aspects in each case.

Key Words: Basal Cell Carcinoma, Local Recurrence, Histologic Types, Anatomic Site, Tumor Size.